Vitamin E has antioxidant properties and may be effective in treating dark circles caused by hyperpigmentation. Dark circles are medically known as periorbital hyperpigmentation, which can be caused by a variety of factors, such as melanin deposition, exposure of blood vessels under the skin around the eyes, and skin laxity around the eyes. Vitamin E is a fat-soluble vitamin, and its hydrolyzed product, tocopherol, is an antioxidant, which can play a role in delaying skin aging and preventing melanin deposition in medical cosmetology. For melanin deposition periorbital pigmented dark circles under the eyes may have a certain relief effect, should be used in accordance with medical advice. However, note that long-term use of large quantities can cause blurred vision, diarrhea, dizziness and other adverse reactions, allergic to the drug is prohibited. Usually, dark circles have no obvious effect on the health of the organism, and there is a certain relationship with the aging of the organism, it is difficult to completely eliminate through drugs. It is difficult to eliminate them completely with medication. Those who need treatment are advised to consult a doctor in a timely manner and follow the doctor’s instructions to carry out standardized treatment according to the cause of the disease.