One year after the onset of AIDS, some patients are still in the asymptomatic stage, this part of the patient does not have any discomfort, but also need to be regularly reviewed, and generally do not carry out antiretroviral therapy. There is also a part of patients with early onset of AIDS, already in the AIDS stage, its clinical symptoms are more, such as persistent recurrent fever, night sweats, weight loss, chronic diarrhea, some patients will have psychoneurological symptoms, there are generalized lymph node enlargement. Some patients may have various opportunistic infections, such as Pneumocystis pneumonia, cytomegalovirus infection, fungal encephalitis, tuberculous meningitis and various tumors, etc. Therefore, the clinical symptoms are determined according to the stage of AIDS.