The difference between Radix Rehmanniae Pill and Ginseng Ling Baijusan is the efficacy, treating disease, and drug composition. 1. Different efficacy: the efficacy of Radix Rehmanniae Pill is to warm the middle and strengthen the spleen. The efficacy of Ginseng Ling Bai Zhu San is to benefit the lung qi, tonify the spleen and stomach. 2. Indications: Radix Rehmanniae Pill is used for cold pain in the epigastrium (cold pain in the stomach and abdomen), vomiting, diarrhea, and lack of warmth in the hands and feet caused by coldness in the spleen and stomach. Ginseng Ling Bai Zhu San is used for shortness of breath and cough caused by weakness of the spleen and stomach, loose stools (thin and unformed feces), and tiredness of limbs and fatigue. 3. Different drug composition: Radix Rehmanniae Pill is composed of Radix et Rhizoma Ginseng, Rhizoma Atractylodis Macrocephalae (fried), Radix et Rhizoma Atractylodis Macrocephalae (made), Radix et Rhizoma Ginger, Radix et Rhizoma Glycyrrhizae. Ginseng, Poria, Lentinus edodes (fried), Atractylodes macrocephala (fried), Chinese yam, lotus seed, Platycodon grandiflorus, licorice, Semen Coix lacryma (fried), and Semen aristolochiae. The adverse effects of Radix Rehmanniae Pill and Radix et Rhizoma Atractylodis Macrocephalae Pill are not clear, and these two medicines should not be taken by people with cold and fever, and are forbidden for people who are allergic to them. They should be used under the doctor’s supervision.