Orlistat will reduce the body’s caloric intake, among other things, after taking it, so it will be particularly easy to get hungry. Orlistat is commonly available in tablets and capsules and is a potent, long-acting, specific gastrointestinal lipase inhibitor, which exerts its therapeutic effect by inactivating gastric lipase and small intestinal pancreatic lipase. Inactivated enzymes cannot hydrolyze fats in food. The undigested fat cannot be absorbed by the body, thus reducing calorie intake and achieving weight control. Therefore, it is easy to feel hungry after taking the medicine. Orlistat is used in the treatment of obese or overweight people. Adverse reactions include increased gastrointestinal gas, feeling of urgency in bowel movements, increased frequency of bowel movements, steatorrhea, and fecal incontinence. This product is contraindicated in pregnant women, people who are allergic to orlistat, chronic malabsorption syndrome, cholestasis, organic obesity. It should be used rationally under the guidance of a doctor.