Domestic entecavir is approved by the national drug regulatory department on the market, are quality assurance, can achieve good therapeutic effect. Domestic entecavir listing is after the researchers a lot of laboratory research, clinical trials, clinical evaluation and other procedures, and finally approved by the national drug regulatory department listed, are quality assurance, can achieve good therapeutic effect. Entecavir, mainly used for the treatment of chronic adult hepatitis B with active viral replication and persistent elevation of serum transaminases. The most common adverse reactions are dizziness, nausea, headache, and fatigue. Patients should take it under the guidance of a doctor and should not stop taking it without authorization.