Failure to conceive may be caused by female factors or male factors, and requires timely consultation and examination. 1. Female factor: If a woman has various organic diseases such as thin uterine lining, premature ovarian failure, polycystic ovary syndrome, blocked fallopian tubes, etc., it may be difficult for a fertilized egg to be formed or for a fertilized egg to settle and develop inside the uterine cavity, which may cause infertility in a woman. 2. Male factor: when men have various organic diseases such as weak spermatozoa, severe sperm dysplasia, azoospermia, etc., it is difficult for sperm to combine with egg to form a fertilized egg, which may cause male infertility. Failure to conceive, suffering from infertility has more reasons, need to be under the guidance of professional doctors, according to the specific causes of the appropriate treatment.