Follicular hyperplasia of the root of the tongue is commonly associated with hypertrophy of the lingual tonsils or lingual inflammation, etc. Long-term foreign body sensation requires relaxation, active treatment of upper respiratory tract diseases, and removal of external adverse stimuli. Follicular hyperplasia of the tongue root is related to upper respiratory tract infection or lingual inflammation, nodular elevation of the lateral edge of the root of the tongue, often with a foreign body sensation, generally no obvious symptoms can be treated, but need to maintain a good psychological state, eliminate anxiety. The papillitis of the tongue may exist in the mouth with a foreign body sensation, need to actively seek medical treatment, and keep the oral cavity clean and hygienic. If the upper respiratory tract infection, need to treat the upper respiratory tract disease. Long-term follicular hyperplasia of the tongue root with foreign body sensation, need to actively remove the external stimulus, the general prognosis is good, after removing the cause of the disease still exists, it is recommended to carry out a biopsy, to exclude the risk of cancer.