Waking up at 4-5 does not necessarily mean cancer. If cancer is suspected, it may be accompanied by corresponding clinical manifestations, or it may also be accompanied by weight loss, pain, loss of appetite, etc. Psychologically, there may also be anxiety, fear and eating disturbance. If the above symptoms occur, you should be alert to the occurrence of cancer and go to hospital for treatment in time. However, waking up at 4-5 may be caused by many reasons. We should not only be alert to cancer, but also to the following factors: 1. Improper diet before bedtime: drinking strong tea, coffee and other beverages before bedtime may easily lead to insomnia. And eating too much before bedtime will affect the digestion of the stomach and intestines and make it easy to wake up early; 2. Sleep dysfunction: It may be caused by high work pressure, frequent late nights, reversal of biological clock, etc., which leads to insomnia and dreaminess, difficulty in falling asleep and easy to wake up in the morning, etc.; 3. Decrease in melatonin secretion: Melatonin is the human sleep hormone, when melatonin gradually decreases, it will lead to early waking and short sleep time; 4. Menopausal insomnia: endocrine disorders during menopause, nervous system dysfunction, there will be insomnia, dreamy, early awakening symptoms; 5, depression: such as early awakening after the body feels fatigue and weakness, low mood, irritable mood, more pessimistic mood, may be depression factors affecting sleep. In order to prevent early awakening, let yourself have a good sleep, have a regular rest time, avoid staying up late, keep your biological clock, avoid drinking strong tea, coffee and other refreshing drinks before going to bed, dinner can be seven minutes full, and you can also soak your feet before going to bed to promote sleep, etc.