The pain in the lower right side of the abdomen is aggravated at night, which may be related to acute appendicitis, adnexitis, intestinal torsion and urinary stones. 1. Acute appendicitis: metastatic right lower abdominal pain, appendiceal point pressure pain, rebound pain as its common clinical manifestations, the patient is persistent with paroxysmal exacerbation of right lower abdominal pain. 2. Adnexitis: most of the symptoms are pain, which can be unilateral or bilateral lower abdominal pain, persistent pain, aggravated by activity or coitus. 3. Intestinal torsion: Intestinal torsion can cause abdominal pain, which is sudden and persistent severe abdominal pain, often in the umbilicus or small abdomen. 4. Urinary stones: urinary stones may cause abdominal pain, the location of pain according to the stone is located in different parts of the different, the right side of the lower abdomen pain is mostly caused by the right side of the ureteral stones. These are just some of the common causes. The pain in the lower right side of the abdomen is aggravated at night, and if the symptoms are not relieved by bed rest, it is recommended to go to a regular hospital in time to get a clear diagnosis and standardized treatment according to the doctor’s instructions.