The incidence of acute pancreatitis is increasing clinically, and its causes are mainly biliary pancreatitis, hyperlipidemic pancreatitis and overeating and heavy drinking. Nursing care for pancreatitis is very important, and nursing measures are mainly taken for organ function. Because severe pancreatitis may have organ insufficiency or failure, endangering the patient’s life, nursing care should monitor the patient’s heart rate, blood pressure, blood oxygen, respiration, and urine output changes, that is, monitoring the circulatory system, respiratory system and urinary system function changes. In addition, within 72 hours of the onset of pancreatitis, the amount of fluid should be replenished, and while replenishing the fluid, attention should be paid to the occurrence of the patient’s cardiac insufficiency, so it is necessary to record the 24-hour in and out of the volume, including the amount of fluids, urine, stool, gastrointestinal decompression volume. In addition, after the condition is recovered, the patient’s diet should be instructed according to the cause of the disease, for example, in hyperlipidemic pancreatitis, it is necessary to limit the intake of high-fat food, strengthen the exercise, and it is recommended to check the blood lipids regularly, and to go to endocrinology department to treat hyperlipidemia if necessary.