Most of the scattered white spots on esophageal mucosa are related to diet, disease, vitamin deficiency and other factors. Scattered leukoplakia on esophageal mucosa is usually caused by hyperkeratosis of the mucosa, the specific cause of the disease is not known, but it is thought to be related to diet, disease, vitamin deficiency and other factors, which is relatively rare, and the patients mostly have bad dietary habits and consume too spicy and hot food to damage the mucosa of the esophagus, causing esophageal leukoplakia to appear. This disease is a precancerous lesion of esophageal cancer, patients should pay attention to their daily dietary habits and living habits, prohibit spicy, cold and stimulating foods, prohibit smoking and alcohol, to prevent further damage to the esophagus, and at the same time, follow the doctor’s instructions for treatment. If the white spot expands in a short time, hard nodules appear at the base, wart-like protrusions appear or obvious pain occurs, it is recommended to consult a doctor in time to improve the examination to ascertain whether there is cancer.