Generalized weakness after cold and fever, should be under the guidance of the doctor to reduce fever, active treatment of cold, drink more water, eat more vegetables and fruits and so on. Cold and fever can cause generalized weakness, the first step should be fever, if the fever is less than 38 ℃, can be relieved by rest, drink more water, physical cooling, etc., if more than 38.5 ℃, should be under the guidance of the doctor oral antipyretic drugs such as ibuprofen, acetaminophen, etc.. With the improvement of cold, fever and general weakness can be recovered by themselves, during the period, pay attention to eat more nutritious substances, improve resistance, do not eat spicy and stimulating food, do not drink alcohol, eat more vegetables and fruits. If the symptoms fail to improve or even worsen gradually, it is necessary to consult a regular hospital in time and cooperate with the doctor to improve the examination and standardize the treatment.