Anlotinib is also effective against brain metastases. Anlotinib is a small molecule multi-targeting drug that can be applied to a variety of malignancies. The main indications are advanced non-small cell lung cancer, and those with progressive disease after two or more types of chemotherapy can be considered for oral anrotinib. Small cell or non-small cell lung cancer like this one is also more prone to brain metastases. Once brain metastases appear, choosing Anrotinib and then combining it with local radiotherapy to the brain and other comprehensive treatment is effective in controlling the disease development and prolonging the survival. During the use of Anrotinib, some other side effects may occur, such as skin reactions on hands and feet, allergic reactions, liver function damage, etc., which also need to be treated symptomatically.