Hand, foot and mouth disease (HFMD) is an infectious disease caused by an enterovirus and is most commonly seen in children. After a child is infected with HFMD, he or she can develop a rash, mostly on the hands, feet and buttocks. The oral mucosa is broken, and the child may have oral pain causing loss of appetite, drooling, fever, nausea, vomiting, headache, dizziness, easily startled, sleeplessness, and in severe cases, delirium and coma. There are also some children who are infected with the virus but do not show any symptoms of discomfort. As long as the child is infected with HFMD, he or she must be isolated and treated symptomatically according to the severity of symptoms. Patients with severe symptoms in general should be seen promptly for relevant tests and active treatment to control the disease.