The cost of a thyroid puncture biopsy is around$500, which can fluctuate depending on the region and hospital. Thyroid puncture biopsies are performed on thyroid nodules and are usually guided by ultrasound, which allows for a safer and easier detection of the procedure. A syringe with a puncture needle is generally used to aspirate components from the thyroid nodule site, which are then sent to the appropriate department for analysis and evaluation to determine the nature of the nodule in the thyroid. Before having a thyroid puncture biopsy, stop using blood-activating drugs, such as aspirin and salvia, and know your blood count and whether there are any abnormalities in blood clotting, which can affect the procedure. After the operation, you must pay attention to the care to avoid local bleeding, and do not eat spicy and acidic food to avoid stimulating the wound inflammation.