The clinical manifestations of cystic fibrosis are, among others, the following In the respiratory system, the main manifestations are recurrent bronchial infections and airway obstruction. Symptoms can appear within a few days after the birth of a newborn. In the early stages, there can be a mild cough with pneumonia and atelectasis, after which there can be an increased cough, difficulty in coughing up mucous sputum and shortness of breath. Some patients may develop a large amount of purulent sputum, or hemoptysis. When the digestive system is affected, digestive and nutritional deficiencies may occur. In newborns, protein digestion can be affected due to increased intestinal mucus secretion and viscosity, as well as defective pancreatic enzymes, etc. Intestinal obstruction and rectal prolapse can also occur in children. Inadequate pancreatic secretion results in symptoms of indigestion such as abdominal distention, abdominal bulging, and discharge of large amounts of foamy, foul-smelling stools, and even steatorrhea and nitrogen overflow can occur. Reproductive system, when male fibrosis affects the reproductive system, it may block the ducts connecting the testicles and prostate, also known as the vas deferens, so many patients may be accompanied by infertility.