Because the early symptoms of chronic kidney disease are not obvious, so it has been regarded as the “invisible killer”, but chronic kidney disease can still be traced. 1, urine foam, long does not disappear, indicating that the urine excretion of more protein. 2, urine discoloration, a strong tea color, wash meat water-like, soy sauce color or cloudy like rice water, indicating that there may be red blood cells or white blood cells inside. 3, too much or too little urine, the normal daily urine volume in about 1500 ml, if there is no drink too little water, sweating, fever, diarrhea and other factors urine volume suddenly reduced should be abnormal. Urine volume of more than 2500 ml per day should be checked to clarify whether the kidneys and other diseases. 4, increased nocturia, normal people within 60 years of age should not generally have nocturia, if young people have increased nocturia, it is likely to be an early manifestation of poor kidney function. 5, causing edema of the eyelids or face after waking up. 6.Fatigue, weakness and back pain without clear reasons. 7.Increased blood pressure, 5-10% of hypertension is due to kidney lesions. 8.Unexplained anemia, itchy skin, cramps, bleeding gums, etc.