The early symptoms of renal insufficiency are as follows: 1. There may be no obvious symptoms, sometimes you will feel lumbar weakness and loss of appetite. With the aggravation of the disease, many clinical manifestations will appear first of all, edema, initially edema of both eyelids and facial edema, which may subsequently develop into swelling of both lower limbs or even the whole body.2. Hypertension may exist, and high blood pressure will lead to dizziness and headache.3. Severe patients may develop heart failure, heart panic, chest tightness, difficulty in breathing, etc.4. Patients may experience nausea, vomiting, or even bleeding from peptic ulcers. 6. Internal environmental disorders, such as severe hyperkalemia, hypocalcemia, hyperphosphatemia, and metabolic acidosis, may occur. In patients with hepatic insufficiency, loss of appetite, nausea, and vomiting may occur in the early stage, and as the condition worsens, this jaundice, abdominal pain, and ascites condition may occur. In case of severe liver failure, patients may even develop serious conditions such as hepatic encephalopathy and cerebral coma, which may be accompanied by gastrointestinal bleeding, such as vomiting blood and black stools.