Uremia is the fifth stage of chronic kidney disease, the end stage of chronic renal insufficiency, which causes many complications, among which cardiovascular pathology is one of the main and most common complications. The reason considered may be the stimulation of urotoxins, long-term hypertension in kidney patients causes coronary artery atherosclerosis and lumen narrowing, which in turn further leads to coronary heart disease. Uremia can also cause many other serious complications, such as sodium and water retention that can cause the development of heart failure. Hyperkalemia can cause arrhythmias and damage to the heart muscle, and toxin stimulation can also lead to pericarditis and lung infections. These factors further aggravate the occurrence of cardiovascular adverse events in uremic patients and increase the morbidity and mortality rate. In addition, uremia can also cause respiratory, digestive and neurological damage.