Usually, the size of lymph nodes in the neck is 0.2-0.5cm and not easy to be touched, if the patient has 2-3cm lymph nodes in the neck, then he/she has enlarged lymph nodes. There are many reasons for the enlargement of lymph nodes in the neck, such as inflammation, tumor, immune diseases, etc. It is recommended that patients should go to the hospital in time when they have symptoms of 2-3cm lymph nodes in the neck, and then go for targeted treatment after a clear diagnosis is made. 1, Inflammation: If the patient’s cervical lymphatic or adjacent tissues are infected, inflammation of the lymph nodes is possible, which may lead to the enlargement of the lymph nodes. Enlarged lymph nodes are usually soft, with slight pressure, smooth surface and no adhesion. Treatment is mainly anti-infection therapy, if it is a bacterial infection, you can use cephalosporins, penicillins and other antibiotics for anti-inflammatory treatment, usually after a certain period of time, the lymph nodes can be gradually reduced; but there is a special case, that is, Mycobacterium tuberculosis infection, although it is also a bacterial infection, but need to be given to the patient rifampicin, isoniazid and other anti-tuberculosis medication for treatment; if it is a viral infection, you need to apply some antiviral drugs to treat it. In case of viral infection, some antiviral drugs need to be applied to deal with it; 2. Tumor: some patients may have tumors in the cervical lymph, or malignant tumors in other parts of the body have cervical lymphatic metastasis, in which case enlarged cervical lymph nodes may also occur. Enlarged lymph nodes tend to be hard, and some patients may have a rubbery feeling, adhesion with surrounding tissues and not easy to push, generally not accompanied by pressure pain. If this happens, patients should go to Head and Neck Surgery Department in time, and cooperate with doctors to carry out surgical treatment, chemotherapy, radiotherapy, targeted therapy and other anti-tumor treatments after confirmation of diagnosis. Due to different stages and types of tumors, there is a big difference in the treatment plan; 3. Immunity diseases: such as allergic sepsis, systemic lupus erythematosus, connective tissue disease and other immunity lesions, which can also cause the enlargement of cervical lymph nodes. This condition often needs to be effectively controlled by a number of non-steroidal anti-inflammatory drugs, immunosuppressants, glucocorticoids, interferon, and chemotherapeutic agents.