The treatment of coronary artery plaque is mainly to improve lifestyle and drug therapy, and then interventional therapy if the coronary blood flow is seriously affected. 1. Improvement of lifestyle: including ① control of hypertension, diabetes mellitus, dyslipidemia, obesity; ② reasonable diet, such as reducing the total calorie intake, reduce cholesterol and salt intake, etc.; ③ appropriate physical labor and physical activities, in order not to symptoms as the limit; ④ reasonable arrangement of life and work, reduce mental stress. 2. Drug treatment: such as the use of lipid regulating drugs such as atorvastatin, ezetimibe, etc.; anti-platelet drugs such as aspirin, clopidogrel, etc.. 3. Interventional therapy: For severe stenosis caused by plaque, dilatation balloon and coronary stent can be used for expansion. In severe cases, bypass grafting can be performed. Patients with multiple plaques in the coronary artery should consult the cardiology department in time. Aggressive treatment.