There is no best way to change gray hair to black hair at 50 years old. Generally speaking, the appearance of gray hair at 50 years old is a normal physiological phenomenon, no need to worry too much. If you want to change from gray hair to black hair, you can try to take drugs, keep a pleasant mood to improve the method. 1. Medications: If accompanied by symptoms of kidney deficiency, such as premature aging, forgetfulness, lumbar and knee pain and weakness, you can take Zhi Bai Di Huang Pills, Right Angelica Pills and other drugs to improve gray hair. If accompanied by symptoms of labor and blood injury, such as insomnia, forgetfulness, etc., you can take medicines such as Yiqi Nourishing Blood Oral Liquid, Colla Corii Asini Pellets to improve gray hair. If there are only gray hair symptoms, it is recommended that the doctor to determine whether to use drugs, generally do not recommend the use of drugs. 2. Maintain emotional optimism: when a person is in a state of anxiety for a long time, depression and unhappiness, it is easy to liver stagnation, affecting the operation of blood qi, hair can not be nourished will be easy to become white. So you should keep an optimistic mindset, do not get angry too often. It should be noted that the 50-year-old gray hair without other special symptoms, is a normal phenomenon, generally no drug treatment, but if accompanied by kidney deficiency, strain injury and other symptoms, can be standardized under the guidance of a doctor, do not blindly use their own medicines to prevent improper use of medication.