Calf gastrocnemius muscle hypertrophy is usually caused by progressive muscular dystrophy or excessive exercise, calf tumors and other causes. 1. Progressive muscular dystrophy: muscle atrophy, muscle weakness, pseudohypertrophy of calf gastrocnemius muscle and other symptoms usually occur. This disease is a hereditary disease caused by genetic defects, which may affect the motor system, central nervous system and so on. 2. Excessive exercise: Excessive exercise, excessive training of the lower limbs, as well as engaging in frequent violent and excessive weight-bearing exercise of the lower limbs may lead to hypertrophy of the calf gastrocnemius muscle, which can be relieved by some stretching and stretching exercises. 3. Calf tumor: soft tissue tumor or bone tumor at the back of the calf can cause enlargement of the gastrocnemius muscle at the back of the calf, which can cause pain and other compression symptoms. There are other reasons that can cause enlargement of calf gastrocnemius muscle, such as trauma, etc. If accompanied by uncomfortable symptoms, it is recommended to go to the hospital in time, complete the relevant examinations, and follow the doctor’s instructions to carry out targeted treatment after clarifying the cause of the disease, so as to avoid delaying the condition.