Studies have shown that six types of drugs can cause impotence in men, male friends have to be careful, these six types of drugs are: 1, anti-hypertensive drugs lead to ED (impotence) the most reported, it is now generally believed that in the anti-hypertensive drugs, the most commonly caused by ED are mainly diuretics and beta-blockers. 2, very widely used gastrointestinal drugs, cimetidine, ranitidine, nizatidine, etc. are mainly used to treat peptic ulcers, there are more and more case reports that they can cause sexual dysfunction. For example, young men who take cimetidine for a long time may develop ED, loss of libido and breast development. 3, antidepressants. Among the commonly used antidepressants, promethazine, amitriptyline, chlorpromazine, new selective 5-hydroxytryptamine reuptake inhibitors, etc. can cause erectile dysfunction, abnormal ejaculation and lack of libido. 4, psychostimulants and narcotics. The most common are alcohol, nicotine, cocaine, heroin, marijuana, etc. 5, anti-tumor drugs. Anti-tumor drugs on gonadal damage but easily overlooked, including cyclophosphamide, nitrogen mustard, vincristine, cytarabine and other drugs can cause erectile dysfunction or sperm deficiency in men, women will occur menstrual disorders and menopause. 6, prostate drugs. Drugs used to treat prostate enlargement such as 5-alpha reductase inhibitors (trade name: Paulownia) can also have the side effect of erectile dysfunction and reduced ejaculation. In addition, drugs commonly used in the treatment of prostate cancer such as anti-androgen drugs (Fuzeol, etc.) can affect libido, penile erection, and ejaculation by affecting the secretion of androgens.