The etiology of erectile dysfunction is divided into two categories: organic and psychological, where the organic etiology includes vascular, neurological, endocrine and penile factors. However, it should be noted that these high-risk factors are only conclusions and possibilities after statistical analysis, and do not mean that having these high-risk factors will definitely develop erectile dysfunction. 1, age in 1992, the United States National Institutes of Health concluded that age is a close relationship with erectile dysfunction indirect risk factors, with age, the possibility of erectile dysfunction increases. Foreign reports, the prevalence of erectile dysfunction in men aged 20 to 30 years old is 7%, and the prevalence of erectile dysfunction in men aged 70 to 79 years old is 57%. Although the likelihood of erectile dysfunction increases with age, erectile dysfunction is not inevitable in the aging process. 2. Diseases ① The proportion of patients with cardiovascular diseases such as heart disease and hypertension with erectile dysfunction is 39% and 15%, respectively. And erectile dysfunction may be the precursor of systemic atherosclerosis. ②Diabetes is one of the diseases most closely related to erectile dysfunction, and the prevalence of erectile dysfunction in diabetic patients is 23% to 75%. The likelihood of erectile dysfunction in people with diabetes for more than 10 years is one times higher than in people with diabetes for less than 5 years. In addition, poor blood glucose control and smoking increase the likelihood of developing erectile dysfunction. (3) The proportion of chronic renal insufficiency with erectile dysfunction is more than 40%. ④ Hyperlipidemia, the higher the total serum cholesterol, the lower the high close lipoprotein, the greater the possibility of erectile dysfunction. ⑤ Multiple sclerosis, stroke, demyelinating diseases, Alzheimer’s disease and other neurological disorders are related to erectile dysfunction. (6) Endocrine disorders such as hypopituitarism, hypogonadism, hyperprolactinemia, adrenal gland disease, hyperthyroidism, and hypothyroidism are associated with erectile function. (7) Diseases of the prostate and penis are more than 40% likely to be associated with erectile dysfunction. (8) The possibility of ulcer disease with erectile dysfunction is 18%, arthritis, allergies, alcoholic cirrhosis, chronic obstructive pulmonary disease, etc. are closely related to erectile dysfunction. 3, psychological factors psychological diseases such as schizophrenia, depression and the treatment of depression drugs are related to erectile dysfunction. 50% to 90% of depressed patients have a low libido; on the other hand, sexual dysfunction often causes depression, anxiety and other mental abnormalities. 4, medication diuretics, antihypertensive drugs, drugs for heart disease, tranquilizers, antidepressants, hormones, anticholinergics and drugs for ulcer disease may lead to erectile dysfunction. 5, bad lifestyle ① smoking. The prevalence of complete erectile dysfunction in heart patients who smoke and do not smoke is 56% and 21%, respectively; the prevalence of complete erectile dysfunction in hypertensive patients who smoke and do not smoke is 20% and 8.5%, respectively. ②Alcoholism. Alcohol has “improve sex drive, reduce sexual power” said. Foreign research shows that the prevalence of erectile dysfunction in patients with liver disease who are alcoholics and non-alcoholics is 70% and 25%, respectively. And half of them failed to regain erectile function even after years of abstinence from alcohol. (iii) Drug use. A study showed that the prevalence of erectile dysfunction in heroin addicts was 32.2%. 6, trauma, surgery spinal cord injury or surgery, pelvic fracture combined with urethral trauma, transabdominal perineal rectal cancer radical surgery, retroperitoneal lymph node dissection, aortic reconstruction, prostate cancer pelvic radiotherapy and any other trauma and surgery that damage penile innervation and vascular supply are likely to cause erectile dysfunction. Therefore, surgeons should continue to improve their surgical procedures and surgical skills to prevent the occurrence of medically induced erectile dysfunction.