Lymph nodes on the neck of children can be treated clinically according to the size and nature of the lymph nodes. If the lymph nodes are large in size and the inflammatory lymph nodes are enlarged due to local infection, it is suggested that the patient should be given cephalosporin antibiotics to strengthen the anti-infection treatment and promote the faster absorption of the infected lesions in the body, and the enlarged lymph nodes can slowly subside after the inflammation is completely controlled, which can often achieve better treatment results. If the lymph nodes in the neck are enlarged due to tumor lesions, such as malignant tumor of thyroid gland, malignant tumor of nasopharynx, lymphoma, etc., the lymph nodes in the neck can be examined by ultrasound-guided needle aspiration or biopsy, and surgery can be performed as soon as possible after the nature of the lesion is clarified to remove the lymph nodes and the primary malignant tumor, and chemotherapy can be combined with the treatment after surgery if necessary. Most of the patients can achieve certain therapeutic effect.