The skull plays a big role in building a solid defense wall for the brain tissue so that the intracranial tissues can function and work normally. However, when the skull defect occurs due to an accident, the shape of the patient’s head is changed and the intracranial tissues may be attacked by the outside world at any time because there is no external protection, which has a great impact on human health and cannot be ignored. Can the bulge of the skull defect be concave? After a serious cranial defect, the defective part will collapse or bulge, and the external appearance of the head is very unattractive, and with the change of intracranial pressure and cerebrospinal fluid, sometimes it may be bulging and sometimes it is concave. It greatly affects the life and work of patients. The correct solution for cranial defects is to have cranial repair surgery in time, so as to restore the anatomical structure of the skull, restore the beauty of the skull shape, increase safety and improve the patient’s self-confidence. However, it is important to choose good repair materials for skull repair surgery, as bad materials will have poor postoperative results. Nowadays, many local hospitals use titanium mesh material for surgery. Compared with the past material, titanium mesh material has certain progress, but there are still certain defects and shortcomings, such as postoperative infection, rejection reaction, cutting pain, postoperative sensitivity to external hot and cold environment, and exposed titanium mesh material, etc. In view of the problems with titanium mesh materials, a new type of polymer material has emerged, which is polyether ether ketone PEEK material, which has excellent properties and makes up for the various shortcomings of titanium mesh materials. In addition, we have introduced the concept of cosmetic surgery, and the postoperative results are very natural and beautiful, and patients are very satisfied.