Chemotherapy for lung cancer generally does not need anesthesia, but some special cases need anesthesia, such as malignant pleural effusion of lung cancer, when doing thoracic perfusion chemotherapy, anesthesia is needed to do local anesthesia for chest wall, in order to make puncture and tube placement. Chemotherapy for lung cancer is mostly given by intravenous drip or oral way, such as pemetrexed, paclitaxel, cisplatin, etc. Most of the chemotherapeutic drugs are given by intravenous drip, and a few oral chemotherapeutic drugs, such as etoposide capsule, are given by direct oral way, which will not cause serious pain in the process of chemotherapy, and anesthesia is not needed. Before doing thoracic perfusion chemotherapy for lung cancer, it is necessary to do thoracic puncture and tube placement, and the process requires local anesthesia at the puncture site, and there is no need for anesthesia during the actual thoracic perfusion chemotherapy. Chemotherapy for lung cancer must be carried out under the guidance of specialists and must not be applied without authorization. Adverse reactions such as nausea and vomiting are common with chemotherapeutic drugs, so it is recommended to eat less and more meals during chemotherapy, and have a light and easy-to-digest diet. It is recommended that patients should evaluate their conditions under the guidance of specialized doctors and choose appropriate treatment plans.