Helicobacter pylori positive need to take medication under the guidance of a doctor for treatment, commonly used is triple therapy and quadruple therapy. 1. Triple therapy refers to choosing a proton pump inhibitor and two antibiotics. Commonly used proton pump inhibitors are omeprazole, pantoprazole, etc. Commonly used antibiotics can be amoxicillin, clarithromycin and metronidazole, etc. 2. Quadruple therapy refers to the choice of a proton pump inhibitor, a bismuth agent, two antibiotics, commonly used proton pump inhibitors such as omeprazole, pantoprazole, etc., bismuth agent has colloidal bismuth pectin, bismuth potassium citrate, etc., antibiotics can choose amoxicillin, metronidazole, clarithromycin and so on. The treatment course of triple and quadruple is usually 10-14 days, and the medication must be taken on time and according to the dosage as prescribed by the doctor before use. If there is any discomfort, it is recommended to consult a doctor in time to avoid delaying the condition.