High-density nodules in the lungs are more serious when they are 22 mm in diameter, and the severity needs to be considered in the context of the specific condition, with a fair prognosis if benign nodules are considered and a poor prognosis if malignant nodules are considered. Lung nodules are swellings found on lung imaging that are denser than the lung tissue. Lung nodules are categorized into benign and malignant nodules based on the nature of the nodule. Benign nodules such as tuberculosis ball and pulmonary fibroma generally have a relatively good prognosis. Malignant nodules, i.e. lung cancer, have a close relationship between their prognosis and disease progression, with early prognosis being acceptable and late prognosis being poor. Early malignant nodules, with small diameter and without regional lymph node metastasis and distant metastasis of the tumor, can be treated by radical surgical resection, and the prognosis can be good. In advanced malignant nodules, the diameter of the tumor is larger, lymph node metastasis and distant metastasis may occur, and the prognosis is relatively poor. If you find lung nodules with a diameter of 22mm, it is recommended to consult a doctor in time and standardize the treatment after a clear diagnosis, so as to avoid delaying the condition.