There is no clear clinical data indicating the precursor of cholangiocarcinoma, and early intrahepatic cholangiocarcinoma patients do not have special clinical symptoms, and some patients may have jaundice. Some patients may have jaundice, and with the development of the disease, they may also have abdominal pain, skin itching, weight loss and so on. Usually, patients with intrahepatic cholangiocarcinoma do not have special symptoms in early stage, and the symptoms may not appear until the lesion increases in size, which induces bile duct obstruction and leads to cholestasis. And with the development of the disease, patients with intrahepatic cholangiocarcinoma will have abdominal pain, fatigue, epigastric mass, jaundice, fever and other symptoms. If it is hilar or extrahepatic bile duct cancer, the jaundice appeared in patients will deepen with the prolongation of time, and they may also have grayish and light-colored stools, and some patients may also show itching of skin and deep yellow urine. Some patients may also have itchy skin, deep yellow urine, etc. Patients may also have tiredness and weight loss. If the patient also has symptoms such as right upper abdominal pain and chills, it means that the patient may be accompanied by cholangitis. It is recommended that patients should be alert to cholangiocarcinoma and other diseases when the above abnormalities occur, and actively treat them after clear diagnosis.