When the testicles are irregularly shaped, the possible causes are: 1. When epididymitis or orchitis occurs, local swelling can occur, and when touched, the testicles can be felt to be enlarged and irregularly shaped, and accompanied by pain when touched, scrotal distension and other discomfort. It is recommended to perform ultrasound examination to clarify whether there is testicular enlargement, testicular inflammation and other manifestations. 2. Testicular sphingomyelitis, the presence of fluid in the sheath cavity wrapped around the periphery of the testicle, when the testicle can appear enlarged. It is possible that the testicle may not be clearly palpable when touched. There is usually no obvious pain, and its effusion may gradually increase in volume over time. Ultrasound examination of the testicles is recommended to rule out syringomyelia.3. Tuberculosis of the testicles or epididymis may result in focal nodules, which can be felt as raised nodules with irregular shape when touched. In the acute stage, there may be pain, but in the chronic stage, there is usually no pain. In the acute stage, there may be pain, but in the chronic stage, there is usually no pain. Further ultrasound and tuberculin examination are needed.4. Tumors of the testicles may appear with unsmooth surface, irregular shape, increased density and hard texture of the testicles, vaginal swelling, pain and other discomforts. It is recommended to further investigate the testicular tumor index and testicular ultrasound examination to clearly exclude whether there is a tumor lesion.