If a patient has clinical symptoms of precordial pain during sleep, the following causes should be considered: First, it is usually because the vagus nerve pull reflex is triggered during sleep, and the vagus nerve excitability is too high, it will lead to symptoms of precordial pain. Usually the patient has cardiogenic diseases, such as coronary angina, acute myocarditis, or pericarditis, or infective endocarditis, various factors leading to malignant Cardiac arrhythmia, heart failure, all will have symptoms of precordial pain during sleep. Second, if the patient has infectious diseases of the respiratory system, such as massive lung infection, pleurisy, there will also be symptoms of precordial pain during sleep. Third, if the patient has intercostal neuralgia or herpes zoster pain, these chest wall diseases may also trigger the patient’s tensor reflex during sleep, resulting in pain and discomfort in the precordial area during sleep.