Forefoot callus may be caused by callus, plantar warts and other diseases, can be improved through medication, physical therapy and other methods. 1. callus: the foot is subject to long-term pressure, constant friction and other factors may lead to the occurrence of forefoot callus, the main clinical manifestation of unclear boundaries, yellow flat or mound-shaped elevation, limited thickening of the corns plate (i.e. callus), the corns plate is often the center of the thick edge of the thin, hard, smooth surface, the serious ones can be chafed, usually no self-awareness of the symptoms. The callus can be removed by local soaking in warm water, or externally applied with exfoliant (e.g., Vitamin A cream, etc.), and at the same time, pay attention to the protective measures, such as trying to wear suitable and soft shoes, and soak your feet in warm water before going to bed, to promote the blood circulation of the feet. 2. Plantar warts: Human papilloma virus infection in the forefoot can cause plantar warts. It can be manifested in the forefoot callus, characteristic performance is the foot metatarsal part of the appearance of a clear border round or oval keratinized hyperplasia lesions, surface rough uneven, no normal texture, around the thickening of the keratin ring around, cut the surface of the callus of the cuticle, you can see loose keratin core and because of the rupture of capillaries, the blood extravasation of the formation of the small black spots, the patient is often accompanied by a varying degree of pain. The treatment of plantar warts is mainly through freezing, electrocautery, scraping and laser physical therapy methods to help remove, but also can be applied locally vasic acid ointment, fluorouracil ointment, imiquimod ointment and other medications to help treatment. To summarize, patients are advised to go to the hospital in time to clarify the cause of the disease, and use the above methods of treatment under the guidance of physicians.