The general method of applying rhubarb and mannite externally is to grind it and apply it, and it is recommended to use it under the guidance of a physician, and do not use it on your own. Rhubarb is a plant-based traditional Chinese medicine, cold in nature, bitter in taste, belonging to the spleen, stomach, large intestine meridian. The specific method of applying this product externally is to grind it and apply it externally. Its efficacy is to cool the blood and detoxify the toxin (refers to the treatment of blood-heat and toxin impregnation), diarrhea and attack the accumulation of stagnation, expel stasis and pass the meridians (to remove stasis of blood and dredge up the meridians), clear heat and diarrhea of fire (to remove the body’s heat evils and fire evils), and is mainly used in the treatment of burns, dysentery due to dampness and heat (dysentery due to dampness-heat evils), constipation with accumulation of stagnation, and jaundice. The adverse effects of Rhubarb are not clear at present. Precautions are caution for those with weak spleen and stomach, and contraindicated during lactation, menstruation, and pregnancy. Mangnit is a mineral-based Chinese medicine, cold in nature, salty and bitter in taste, and belongs to the stomach and large intestine meridians. The specific method of applying this product externally is to grind it and mix it. Its efficacy is to moisten dryness and soften hardness, clear heat and eliminate swelling, diarrhea and attack accumulation, and treat stagnation and constipation, redness of the eyes, carbuncle sores and swelling pain, sore throat, mouth sores and so on. Its adverse effects are not yet clear. Pregnant women should be cautious; it should not be used with sulfur rhubarb and sanleng. If you need to use rhubarb and mangosteen, you should follow the doctor’s instructions to use the drug, do not apply on your own to avoid causing adverse consequences.