Amlodipine mesylate tablets need to be under the guidance of a doctor can be replaced with amlodipine benzenesulfonate, has a similar such effect. Amlodipine mesylate and amlodipine benzenesulfonate belong to the same class, the two are only in the structure of the slight difference, can be used for hypertension and coronary heart disease treatment, the same dose of the two drugs to lower blood pressure effect is similar. Amlodipine benzenesulfonate belongs to the calcium antagonist, mainly through the dilation of peripheral blood vessels to reduce blood pressure, but also on the coronary artery has a certain effect of dilation, can also be used in the treatment of coronary heart disease. Adverse reactions include lower limb edema, dry stools, flushing, reactive tachycardia, gingival hyperplasia, etc. It is contraindicated in patients who are allergic to the components of the drug or hypotensive. Patients with hypertension should choose amlodipine benzenesulfonate under the guidance of a physician, paying attention to the dose and dosage form of the drug. In case of discomfort, consult a doctor promptly.