Elevated blood pressure in the second half of the night can take drugs, self-adjustment, if necessary, call an ambulance. 1. Taking medication: If you are diagnosed with high blood pressure and need to take medication, elevated blood pressure in the middle of the night may not be enough to take the dose of medication, and the dose should be increased appropriately. Commonly used antihypertensive drugs have five categories: angiotensin-converting enzyme inhibitors, angiotensin 2 receptor antagonists, diuretics, beta-blockers, calcium antagonists. For example, chlorosartan, hydrochlorothiazide, furosemide, metoprolol, bisoprolol, nifedipine, lasixedipine and so on. 2. Self-adjustment: If there is a sudden increase in blood pressure at night, braking is recommended and activity is not recommended. 3. Timely consultation: If there is a sudden increase in blood pressure, you can take captopril, nifedipine extended-release tablets to lower blood pressure in an emergency, if the patient is combined with a degree of severe chest pain, chest tightness, you should call an ambulance or emergency medical care in a timely manner. Drugs should be used under the guidance of a physician.