In the face of children and adolescents with diabetes only we can not think of. 1. When hypoglycemia occurs in younger children, cognitive function and neuropsychological behavior are impaired, so they cannot control blood glucose too strictly, and the goal of blood glucose control gradually approaches that of adults as they grow older. 2. Insulin is the first choice for type 1 diabetes, and there may be a “honeymoon period” of up to 2 years after diagnosis, when only a small amount of insulin is needed to control blood glucose well, but intensive treatment is needed after the “honeymoon period”: long-acting basal insulin analogues + rapid-acting insulin analogues can be used. After the “honeymoon” period, intensive treatment is needed: long-acting basal insulin analogue + fast-acting insulin analogue injection at mealtime, or continuous subcutaneous insulin injection (insulin pump) therapy. 3, type 1 diabetes pay attention to screening autoimmune thyroid disease (15-30% of type 1 diabetes patients combined with autoimmune thyroid disease); for recurrent hypoglycemia and low insulin needs of type 1 diabetes need to screen adrenal cortical function. 4.Pay attention to lipid and early kidney damage starting at puberty to prevent atherosclerosis and renal and retinal lesions. 5. For severe disease (e.g. ketoacidosis. Glycosylated hemoglobin greater than or equal to 9%) of children with type 2 diabetes mellitus should be treated with insulin. When the blood glucose control reaches the standard, then consider leaving insulin. 6. Islet function test and insulin antibody test can help to distinguish children with type 1 and type 2 diabetes. 7. There are differences in diet and exercise for children and adolescents with diabetes at each age, which need to be adjusted under the guidance of professional doctors. 8, cold and fever, abdominal pain and diarrhea and other small problems that often occur in the normal population may cause big problems: such as dehydration leading to hyperglycemic hypertonic state; poor feeding inducing diabetic ketoacidosis. Another example is that we do not prepare them with antipyretic, antiseptic and antiviral drugs suitable for children and adolescents with diabetes. 9. Emotional psychosocial problems caused by insulin injection and inability to eat at any time like other children (we did not prepare them junk food suitable for children and adolescents with diabetes).