Nifurtimox can not be inserted too dry, it is recommended to adjust the mind as well as replace other drugs. 1. Adjusting the mind: If a woman is too nervous, it may cause the vagina to be tense, so when applying the medicine vaginally, she needs to pay attention to relaxing the mind by taking deep breaths, which will help promote the opening of the vaginal opening and the smooth application of the medicine. 2. Changing drugs: If you still can’t take the medicine through these two ways, you can also change to other drugs, such as metronidazole vaginal gel, with the consent of your specialist. Common adverse reactions to Nifurtil include mild vulvar burning and vaginal dryness, as well as nausea, etc. Those who are allergic to the drug are prohibited from using it. In addition, the application of nifurtimox carries certain risks, and patients are advised to use it under the guidance of a specialist.