The fourth positive item in the hepatitis B two-way test means that the e antibody is positive, which means that if there is a hepatitis B infection, the virus is less infectious, less able to replicate, and less contagious. It means that if you have hepatitis B infection, the virus is less infectious, less able to replicate, and less contagious. The most common type of hepatitis B is a combination of item 1 and item 5 positivity, which is commonly referred to as a minor triplet. This means that the hepatitis B virus is infected but is not very infectious and has a low replication capacity. The presence of both item 2 and item 5 positivity indicates that the body is not currently carrying the hepatitis B virus, is not infected with hepatitis B, and has developed immunity to the hepatitis B virus. If you have a positive item 4 and item 5 alone, but everything else is negative, you are not currently infected with hepatitis B and have had previous hepatitis B infection.