The statement that three categories of people can not take Prilosec is unscientific, but renal artery stenosis, hyperkalemia, pregnant women, and people who are allergic to any component of the product belong to the group of people who are contraindicated to the drug and can not take the drug. Prilosec drugs can inhibit the conversion of angiotensin 1 to angiotensin 2, thus playing a role in lowering blood pressure, lowering protein, inhibiting inflammation, improving cardiovascular effects, clinically used in hypertension, heart failure and other diseases. 1. Renal artery stenosis crowd: if the patient has renal artery stenosis, oral prilosec drugs will make the patient’s renal blood flow decrease, the contraction of the glomerular arteries to make the glomerular intracapsular pressure drop, will accelerate renal failure. It is recommended that patients who can suffer from renal artery stenosis should check the renal artery ultrasound to clarify the condition before using the drug. 2. Hyperkalemia people: patients with hyperkalemia should promote the discharge of potassium, but Prilosec will inhibit aldosterone secretion, aldosterone has the role of potassium-preserving is not conducive to the discharge of potassium. 3. Pregnant women: the pharmacological components of Prilosec can pass through the placenta and cause fetal malformation, so Prilosec is not recommended for pregnant women. Side effects of Prilosec include skin rash, hypotension, palpitations, nausea, dysgeusia, anemia, edema, cough, and renal function abnormalities. It is recommended that patients should consult their doctors and read the instructions of the drugs before taking Prilosec, and should not use the drugs blindly.