Whether creatinine 300 μmoI/L will remain usually depends on its etiology and treatment effect. If the creatinine is elevated due to acute kidney injury, it may return to normal after removing reversible factors; if it is chronic renal insufficiency, the creatinine may be maintained at the current level after active treatment, but it cannot be maintained if the treatment is not effective, the renal function deteriorates, and the creatinine is elevated progressively.
1. Acute kidney injury: If acute kidney injury is caused by insufficient perfusion of renal precursors such as insufficient volume, renal artery stenosis, creatinine level may gradually decrease after treatment to restore perfusion. Or if acute kidney injury is caused by post-renal factors such as urethral obstruction, ureteral obstruction, bladder tumor, etc., the creatinine level can also decrease gradually after the obstruction is lifted. Creatinine will not remain unchanged at this time.
2. Chronic renal insufficiency: if the chronic renal insufficiency is caused by organic damage of glomerulus itself, the damage of kidney is usually irreversible, and the creatinine level may be maintained at the present level if it is treated actively; if the treatment effect is not good, the disease progresses and the renal function deteriorates, the creatinine value will be increased further, and the creatinine value can not be maintained at this time.
If patients find creatinine increase, it is recommended to go to regular hospitals in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or therapy under the guidance of the doctor.