Adults with a fever of 38.9 ℃ can be given diclofenac sodium extended-release tablets or acetaminophen and other drugs to lower the temperature, while actively identifying the cause of the fever. Body temperature of 38.9 ℃ is high fever, prolonged duration can seriously affect the patient’s quality of life, may be accompanied by fatigue, loss of appetite and other uncomfortable symptoms, may also lead to organ function damage, need to be promptly cooled down the treatment of commonly used drugs such as diclofenac sodium extended-release tablets, acetaminophen and other drugs. For those who have contraindications to the above drugs, such as severe thrombocytopenia or allergy patients, can be given hydrocortisone and other glucocorticoids to lower the temperature. At the same time of drug cooling, can also be given warm water bath for physical cooling treatment. Cooling treatment is only symptomatic treatment, but also need to further improve the blood routine, calcitoninogen, C-reactive protein, serum amyloid A, blood culture, urine culture, sputum culture, stool culture, chest CT and other related examinations to clarify the causes of fever, and then target the cause of the treatment. It is recommended that the patient should consult a doctor in time, actively clarify the cause of fever, and at the same time, dynamically observe the temperature change, drink more water, and if necessary, intravenous infusion of saline and other rehydration therapy.