Mucositis of the terminal ileum may be due to non-infectious or infectious factors, and can be treated by immunosuppressive therapy and anti-infectious therapy. 1. Non-infectious factors: may be due to Crohn’s disease, ulcerative colitis, should follow the doctor’s instructions to standardize the use of drugs to inhibit the immune response: common use of glucocorticosteroids, such as prednisone, but also the use of aminosalicylic acid preparation, etc., need to be based on the patient’s condition of the further choice of drugs. 2. Infectious factors: may be due to bacteria, viruses and other causes, need to carry out bacteriological examination, clear pathogenic bacteria. If the ileocecal terminal mucositis caused by Escherichia coli, follow the doctor’s instructions to standardize the use of antibiotic treatment, such as amoxicillin, ceftriaxone, etc.; if Mycobacterium tuberculosis caused by the mucositis of the ileocecal terminal mucositis, follow the doctor’s instructions to use anti-tuberculosis drugs, such as isoniazid, rifampicin and so on. In daily life, ileocecal terminal mucositis eat more light, easy to digest food, drink more water, avoid smoking and alcohol, keep bowel movement, are helpful in the treatment, if the patient is not feeling well in time to see a doctor.