Herpes labialis is a common clinical condition that can occur in both men and women, but is relatively common in women. The basic cause is infection with the herpes simplex virus, and a variety of triggering factors cause the body’s immune system to decline when the infection is prone to occur, resulting in herpes labialis. There are many triggers for herpes labialis in women, especially women who have physiological periods, when their body resistance may be reduced, and some women may have irregular menstruation, dysmenorrhea, and other gynecological diseases that can lead to low immunity, which are triggers for herpes labialis in women. In addition, there are also triggers that can happen to anyone, such as fatigue, poor mental health, stress, and colds. Overwork at work and school, or mental tension, anxiety, stress, and getting wet and cold can cause a decrease in body resistance, which can increase the chances of herpes simplex virus infection. Herpes simplex virus can be transmitted through direct contact with droplets, saliva and herpes fluid, or indirectly through contact with contaminated dishes and clothing. Therefore, patients with herpes labialis should avoid scratching the affected area to prevent infection.