Severe skin allergies with redness, swelling and burning are caused by allergic reactions after contact with allergenic substances, and need to be relieved through general treatment and medication under the guidance of a doctor to promote the improvement of allergic symptoms. 1. General treatment: It is recommended to immediately stop further contact with the allergic substances, and at the same time, cold towels can be used to alleviate the discomfort. Rest, avoiding spicy and irritating food, and abstaining from alcohol and smoking can help to improve the symptoms. 2. Medication: Patients can apply glycerine lotion on the local skin to reduce the redness, swelling and burning of the skin, and can also take oral anti-allergy drugs such as loratadine and cetirizine to improve the symptoms of allergy. If necessary, short-term oral methylprednisolone and other hormone therapy. Patients who are allergic to drugs are prohibited from using them. It is recommended to consult a doctor in case of severe allergy, redness, swelling and burning of the skin, and follow the doctor’s instructions to standardize the treatment.