Tumors in the proximal femur and distal femur, where the function of the artificial prosthesis is more ideal, can be preferred; tumors in the proximal tibia and proximal humerus, where the function of the artificial prosthesis after replacement is poor, can choose prosthesis replacement or microwave in situ inactivation according to the scope of the specific tumor and the psychological needs of the patient; tumors in the distal tibia, elbow joint, distal radius, scapula, etc., where the artificial prosthesis is not yet mature, and microwave in situ inactivation technology is more advantageous. Chen Bingyao, Department of Orthopaedics, The First Affiliated Hospital of the Chinese People’s Liberation Army General Hospital For tumors of the long bone (femur, tibia, ulnar radius) backbone, prosthesis replacement is not recommended because of the large trauma and unsatisfactory postoperative function of the whole bone prosthesis, and microwave in situ inactivation is recommended.