If there is an elevation of white blood cells or neutrophils in the blood, it means that the cold is caused by bacterial infection, and the effect of taking cold medicine alone is often not good, so antibiotics must be used for treatment. If there is no allergy to penicillin, you can take oral amoxicillin or amoxicillin clavulanate potassium, if there is allergy, you can switch to cephalosporin antibiotics, such as cefixime, cefradine. If all of the above drugs are present as allergies, macrolide antibiotics, such as azithromycin, can also be used to treat bacterial infections. If a chest radiograph or CT is done and a cold-induced lower respiratory tract infection occurs, such as bronchitis or pneumonia, you should be hospitalized for treatment. The situation is more serious and the effect of oral medications is often not enough, so you need to choose the appropriate antibiotics or antiviral drugs for intravenous drip treatment according to the type of infection.