Glioma is a common primary malignant tumor in the brain. Due to the diversity and complexity of gliomas in imaging manifestations, some gliomas are not particularly typical in MRI or CT, which makes the imaging diagnosis of glioma difficult. Although the general principle of glioma treatment is based on surgery and combined with radiotherapy, the treatment plan that the patient receives may be different from that recommended by the guideline due to the specificity of each patient. Moreover, glioma is prone to recurrence after treatment, and the diagnosis and treatment of recurrent tumors are even more difficult, and doctors with different professional backgrounds do not have the same recommendations for treatment plans. The complexity in diagnosis and treatment of gliomas, the wide variety of patient conditions, and the differences in the intellectual backgrounds of doctors make the diagnosis and treatment of gliomas extraordinarily complicated. In response to the complexity of glioma treatment, many hospitals have developed a multidisciplinary diagnosis and treatment (MDT) model for gliomas in order to provide optimal treatment for patients with gliomas and to achieve the best therapeutic results. Multidisciplinary diagnosis and treatment of glioma is a diagnosis and treatment model in which experts from multiple related disciplines discuss and formulate the most appropriate treatment plan according to the actual situation of the patient and the actual state of the glioma, and the experts from the corresponding disciplines implement the plan. Due to the limitations of single-discipline diagnosis and treatment, the multidisciplinary diagnosis and treatment of glioma includes experts from multiple disciplines, such as neurosurgery, imaging, pathology, radiation oncology, medical oncology, etc., which are involved in the whole process of diagnosis and treatment of glioma. Whether it is a suspected glioma case or a recurrent or difficult glioma case, experts from different disciplines will discuss and analyze the case from different professional backgrounds and perspectives, and finally reach a consensus to form a complete treatment plan for glioma that is suitable for the patient. Therefore, for the diagnosis and treatment of glioma, especially for complicated and difficult gliomas, the best treatment results are most likely to be obtained through the multidisciplinary diagnosis and treatment model of glioma in the hospital, where specialists of different backgrounds in multiple related fields discuss and formulate the optimal plan, and the relevant specialists carry out the relevant diagnosis and treatment plan.