With the continuous improvement of people’s living standards, the popularization of knowledge of medicine and health, as well as the reform of the public health care system, many families are equipped with daily medication to meet the small illnesses and injuries of self-medication, both convenient and timely, but also affordable. In ensuring the safety and effectiveness of medication should pay attention to several issues: 1, to prevent drug abuse. Abuse of drugs is regardless of the condition, the object of the drug (elderly, adults, children), the performance of the drug and arbitrary use, this practice is ineffective, prolong the treatment time, or delayed treatment to make the condition worse, causing pain to the patient. 2, as little as possible, the combination of drugs. Some drugs are used in combination with each other to improve the efficacy; some drugs are used in combination with each other to reduce the effect, so that the efficacy is reduced, or toxicity increased. Therefore, family medicine is best to use a single product or two kinds of drugs used jointly enough. 3, according to the instructions for the use of drugs, do not ignore the precautions on the packaging of drugs, measure the use of a drug, can not only look at its method of use and purpose, for non-professional members of the family, the precautions are more important, which is a guarantee of safe and effective use of medication. 4, to prevent allergic reactions to the drug. Anyone who is allergic, or has a history of drug allergy in the past, taking drugs should be extra careful, especially sulfonamides such as cotrimoxazole, analgesic analgesic painkillers. Those who have a clear history of allergy to a particular drug in the past should be prohibited from using it again.